Quick answer
Alpha GPC and CDP choline (citicoline) are both compounds that provide choline, an essential nutrient. Alpha GPC is roughly 40% choline by weight, while citicoline is roughly 18% choline by weight and also provides cytidine. They're sold as capsules, such as Alpha GPC 600mg and CDP Choline 300mg.
Choline
An essential nutrient
Alpha GPC
About 40% choline by weight
Citicoline
About 18% choline by weight, plus cytidine
Food sources
Eggs, liver, meat, fish, soybeans
What is choline?
Choline is an essential nutrient that your body needs but can't make in sufficient amounts on its own. Australia's NHMRC sets an Adequate Intake of 425mg a day for women and 550mg a day for men. Eggs, beef liver, meat, fish and soybeans are rich food sources.
Alpha GPC vs CDP choline at a glance
| Alpha GPC | CDP Choline (Citicoline) | |
|---|---|---|
| Full name | L-alpha-glycerylphosphorylcholine | Cytidine 5'-diphosphocholine |
| Choline by weight (approx.) | About 40% | About 18% |
| Also provides | Glycerophosphate | Cytidine |
| MAYN product | Alpha GPC 600mg, 90 capsules | CDP Choline 300mg, 90 capsules |
How to compare choline supplements
- Check the compound and amount per serve.
- Work out the approximate choline content using the percentages above.
- Compare price per serve.
- Remember food sources such as eggs when thinking about your total choline intake.
Tip: Two eggs provide roughly 300mg of choline, a useful reference point.
Frequently asked questions
Is CDP choline the same as citicoline?
Yes. CDP choline and citicoline are two names for the same compound.
Which has more choline, Alpha GPC or citicoline?
By weight, Alpha GPC contains more choline (about 40%) than citicoline (about 18%).
Is choline a vitamin?
Choline is an essential nutrient. It's often grouped with the B vitamins, but it isn't officially classified as a vitamin.
Keep reading
This article is general information only and is not medical advice. Always read the label and follow the directions for use. Dietary supplements should not replace a balanced diet. If you are pregnant, breastfeeding, taking medication or have a medical condition, speak with your doctor or pharmacist before taking a new supplement.
