Quick answer
"Bisglycinate" means a mineral is bound to two molecules of the amino acid glycine. These are called chelated minerals. Iron bisglycinate, copper bisglycinate and magnesium glycinate are common examples, and they're often chosen as an alternative to mineral salts such as sulfates or oxides.
Bis
Two
Glycinate
Bound to glycine, an amino acid
Chelate
A mineral held by an organic molecule, like a claw
Examples
Iron, copper, magnesium, zinc bisglycinate
What is a chelated mineral?
The word chelate comes from the Greek for "claw". In a chelated mineral, the mineral atom is held by an organic molecule (in this case glycine) at more than one point. Bisglycinate simply tells you there are two glycine molecules attached.
Bisglycinate vs other mineral forms
| Form | What it is | Common examples |
|---|---|---|
| Bisglycinate / glycinate | Mineral bound to glycine | Iron, copper, magnesium, zinc |
| Sulfate | Mineral salt with sulfate | Ferrous sulfate, zinc sulfate |
| Oxide | Mineral bound to oxygen | Magnesium oxide, zinc oxide |
| Citrate | Mineral bound to citric acid | Magnesium citrate, calcium citrate |
| Gluconate | Mineral bound to gluconic acid | Zinc gluconate, ferrous gluconate |
Each form contains a different percentage of the actual mineral by weight, which is why labels may list the compound and the elemental amount separately.
Elemental amount vs compound amount
A label might say "iron (as iron bisglycinate) 25mg". The amount in brackets tells you the form; the number usually refers to the elemental mineral. If a label lists only the compound weight, the actual mineral content will be lower.
Tip: When comparing mineral supplements, compare the elemental mineral per serve, not the weight of the compound.
Why people choose bisglycinate forms
Bisglycinate minerals are popular because they're a well-defined, consistent form and are often described as gentle. Whichever form you choose, follow the label directions and speak with your healthcare professional, especially for iron, which should only be taken when needed.
Frequently asked questions
Is glycinate the same as bisglycinate?
They're closely related terms. Bisglycinate specifically means two glycine molecules are attached to the mineral; glycinate is often used more loosely for the same thing.
Is bisglycinate vegan?
Glycine is usually produced synthetically, so bisglycinate minerals are generally vegan. Check the capsule shell and other ingredients.
Should I take iron without a blood test?
Iron supplements should only be taken when needed. Talk to your doctor, who may suggest a blood test first.
Keep reading
This article is general information only and is not medical advice. Always read the label and follow the directions for use. Dietary supplements should not replace a balanced diet. If you are pregnant, breastfeeding, taking medication or have a medical condition, speak with your doctor or pharmacist before taking a new supplement.
